Oxygen wound therapy: The clinical and cost impact of using topical haemoglobin spray (Granulox‰)
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Photoacoustic imaging of real-time oxygen changes in chronic leg ulcers after topical application of a haemoglobin spray: a pilot study.
OBJECTIVE To use a non-invasive measurement of oxygen saturation in chronic leg ulcers after the application of a topical haemoglobin spray to investigate if photoacoustic tomography is able to measure the oxygen saturation and if the stimulated oxygen increase can be demonstrated. METHOD We measured the oxygen saturation of the ulcer tissue in five patients with chronic leg ulcers before app...
متن کاملA topical haemoglobin spray for oxygenating pressure ulcers: a pilot study.
The effect of pressure ulcers on patient quality of life have been recognised as a real problem for many years, and the need for robust and effective management of pressure ulcers is now a prominent national health-care issue. Myriad different interventions exist for the treatment of pressure ulcers, including clinically effective dressings and pressure-relieving devices, yet many pressure ulce...
متن کاملClinical effectiveness of hemoglobin spray (Granulox®) as adjunctive therapy in the treatment of chronic diabetic foot ulcers
INTRODUCTION Hemoglobin spray (Granulox®) comprises purified hemoglobin and is a novel approach for increasing oxygen availability in the wound bed in diabetic foot ulcer patients. Its mode of action is to bind oxygen from the atmosphere and diffuse it into the wound bed to accelerate wound healing in slow-healing wounds. PATIENTS AND METHODS Wound healing outcomes, that is, wound size, pain,...
متن کاملInnovative Medical Technology Overview: Number 006/2016
Granulox ® is a patent-protected first in class medical device. Granulox ® is positioned for use as an add-on therapy to standard care for the treatment of chronic wounds including venous leg ulcers, pressure ulcers and diabetic foot ulcers which have failed to heal after a period of standard care. Beyond administration of the spray, Granulox ® is not expected to impact upon the standard wound ...
متن کاملExpected outcomes from topical haemoglobin spray in non-healing and worsening venous leg ulcers.
OBJECTIVE To evaluate the effect of topical haemoglobin spray on treatment response and wound-closure rates in patients with chronic venous leg ulcers. METHOD A linear regression model was used to forecast healing outcomes over a 12-month period. Simulated data were taken from normal distributions based on post-hoc analysis of a 72-patient study in non-healing and worsening wounds (36 patient...
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تاریخ انتشار 2017